An expert from the FDA explained the benefits and limitations of these two clinical trial formats and how the cancer field can learn from both. The use of single-arm trials, in which all patients ...

Physical therapy is routinely recommended for knee pain attributed to a degenerative meniscal tear, but its efficacy has not been established. We randomly assigned participants 45 to 85 years of age ...

Research indicates that many statin therapy side effects are not supported by evidence, suggesting a need for revised ...

We are witnessing an increasing demand for rapid, rigorous, and generalizable evidence to inform health care systems’ learning and address inefficiencies in the current clinical trials landscape.