The genetic and clinical heterogeneity of breast cancer makes the identification of effective therapies challenging. We designed I-SPY 2, a phase 2, multicenter, adaptively randomized trial to screen ...

Generally, the randomization for phase II trials is between two regimens, tumor response is the end point of interest, and the goal is to determine whether one experimental regimen should be brought ...

Introductory quantitative skills required to conduct experimental research and analyze resulting data. Principles of measurement, modeling of experimental data, and statistical design of experiments.

Sound experimental design is of vital importance when conducting any scientific experiment. Choices made at the design stage have the potential to drastically impact the results of any study. A strong ...

Methods for designing and analyzing industrial experiments. Blocking; randomization; multiple regression; factorial and fractional factorial experiments; response surface methodology; Taguchi’s robust ...

Design of experiments (DoE) is an efficient method for planning experiments. DoE involves intentionally changing one or more input-process factors – also known as independent variables – to observe ...