New work from UC Davis and the University of Utah shows how the 3D structure of DNA inside a germ cell commits it to develop into a sperm cell. The discovery could improve understanding of fertility ...

Epigenetic aging clocks use DNA methylation patterns to measure biological age and predict health risks across human tissues.

Left: Imaging of lamin A/C structures in a physically expanded nucleus from an individual with progeria. Right: Same, but with 3D genomic reads overlaid in their original spatial locations, colored by ...

In biology textbooks and beyond, the human genome and DNA therein typically are taught in only one dimension. While it can be helpful for learners to begin with the linear presentation of how ...

Every cell in every organism on Earth copies DNA the same way. Except one bacterial protein — quietly doing something ...

A robust platform for analyzing 3D genome architecture and epigenomic features enables a deeper understanding of gene regulation in specific cell types. Researchers analyze various aspects of gene ...

Before cells can divide, they first need to replicate all of their chromosomes, so that each of the daughter cells can receive a full set of genetic material. Until now, scientists had believed that ...

While largely unnoticed, phages do not harm humans. On the contrary, these viruses are gaining increasing popularity as biomedicines to eradicate pathogenic bacteria, especially those associated with ...

Researchers showed how what appears to be a tangle of DNA is actually organized into a structure that coordinates thousands of genes to form a sperm cell. The work, published as two papers in Nature ...