The intracellular environment is highly compartmentalized; biomolecules (nucleic acids, proteins, lipids and so on) are spatiotemporally organized to form functional modules, signal pathways and ...

Nucleic acids are complex biological molecules that store and transmit genetic information in all living organisms. They are essential for the survival and reproduction of life on Earth. The two main ...

Guanine quadruplexes (G-quadruplexes or G4s) are unusual nucleic acid structures with distinct biological and chemical functions. They have occupied significant attention in the nucleic acid world ...

Extracted from: Nature (London, England), v. 171, no. 4356 (April 25, 1953). Names of Watson and co-author Sir Francis Crick at end of article. At head of title ...

The discovery of DNA structure by James Watson and Francis Crick in the year 1953 is one of the most revolutionary scientific discoveries to date. However, the research leading to the discovery of ...

In the world of biomolecules such as proteins and the hereditary nucleic acids DNA and RNA, three-dimensional structure determines function. Analysis of the passage of such molecules through nanopores ...

Nucleic acids are essential for all forms of life, and it is found in all cells. Nucleic acids come in two natural forms called deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). Image Credit: ...

DNA is the poster child for high-specificity binding. As long as their base sequences match, two complementary strands of DNA can navigate through a sea of biomolecules, find each other, and hold fast ...

This diagram depicts the chemical structure of pyrimidine, a six-membered aromatic ring with two nitrogen atoms at positions 1 and 3 (highlighted in blue). The remaining positions are occupied by ...

Fully open source model accurately predicts the 3D structures of proteins and biomolecules in silico, and serves as a foundational model for next generation of cutting-edge Protein AI tools The ...

CRISPR has the power to correct genetic mutations, but current delivery methods are either unsafe or inefficient, keeping the technology from reaching its full medical potential. With the power to ...