A decade ago, the Nobel Prize in Chemistry was awarded to a trio of researchers for the development of super-resolved fluorescence microscopy. The announcement at the time stated that the researchers’ ...

The brain relies on real-time delivery of oxygen and nutrients through its microvasculature, which threads through neural ...

Stanford researchers have combined two microscopy techniques to create a one-of-a-kind instrument that can show cell ...

Even those who maintain that super-resolution microscopy is a powerful tool of biological discovery have admitted that it may have a bit of an image problem. For example, in a recent review, several ...

To unravel the complexities of biological phenomena, scientists have long relied on microscopy to visualize the intricate details of their specimens, including tissue architecture, cell morphology, ...

With the rapid revolution in super-resolution microscopy, the resolution of far-field optical microscopy has entered the sub-nanometer era, providing new insights into macromolecules in vitro and in ...

To study living organisms at ever smaller length scales, scientists must devise new techniques to overcome the so-called diffraction limit. This is the intrinsic limitation on a microscope's ability ...

Latest super-resolution microscopy methods now achieve an optical resolution in the range of a few nanometers. This corresponds to a resolution in the range of the size of cellular molecules. However, ...

What is Structured Illumination Microscopy? Structured Illumination Microscopy (SIM) is a super-resolution fluorescence microscopy technique that allows for imaging beyond the diffraction limit of ...

(A–C) Representative images reconstructed by conventional method (left) and new method (right) of microtubules, nuclear pore complexes and F-actin samples. The regions enclosed by the white boxes are ...