CD8 + cytotoxic T lymphocytes (CTLs) serve as central effectors in cancer immunotherapy by directly eliminating tumor cells. However, current clinical therapies face significant limitations. These ...

These results, published in the journal Science Advances, offer hope for a faster therapeutic strategy that could benefit a greater number of patients. Traditionally considered as auxiliary cells, CD4 ...

A substantial proportion of patients with autoimmune diseases experienced a new side effect called local immune effector cell–associated toxicity syndromes (LICATS) after receiving chimeric antigen ...

T cells are essential components of the immune system and play critical roles in immune responses against infections, tumors, and autoimmune diseases. T cells are highly heterogeneous, with distinct ...

CAR T-cell therapy, which transforms patients’ own immune cells into cancer-fighting warriors, has revolutionized how physicians treat cancer, especially blood cancers. “These patients can be cured ...