The interaction between cancer cells and the immune microenvironment leads to immune reprogramming and metastasis. Cancer immunoediting facilitates tumor escape from immune destruction, consequently ...

This article explores how researchers are using spatially resolved methods to explore diverse biological processes from ...

Spatial transcriptomics is a cutting-edge technique that characterizes gene expression within sections of tissue, such as heart, skin or liver tissue. These snapshots provide insights into how spatial ...

Technological development is key to improving the way hematologic cancer is diagnosed and treated. With this vision, the Josep Carreras Leukemia Research Institute is committed to the creation and ...

Spatial transcriptomics provides a unique perspective on the genes that cells express and where those cells are located. However, the rapid growth of the technology has come at the cost of ...

Scaling up single-cell sequencing studies allows scientists to uncover rare cell types, better understand disease states, and track cellular changes over time. However, processing, assaying, and ...

Co-first author Jiyuan Yang, PhD, St. Jude Department of Computational Biology and co-senior and corresponding author Jiyang Yu, PhD, St. Jude Department of Computational Biology interim chair look at ...