Our discovery set comprised 31 pRCCs and paired normal tissue or peripheral blood (Table 1). Three tumours were separate foci from case GK116; these appeared to be grossly distinct lesions and were ...

A new study focused on decoding the genetic chaos found in cancer cells reveals novel biomarkers with the potential to improve the development of precision therapies and treatment selection for the ...

Scientists have revealed how mutations in the BRCA1 gene lead to breast cancer. Findings show that one way BRCA1 mutations cause cancer is by knocking out a powerful tumor suppressor gene known as ...

An international study has identified more than 50 genes on the X chromosome in which mutations may cause poor sperm production. Nearly half of all men with low or zero sperm count have no medical ...

Translocations, in genetics, happen when chromosomes break and the pieces attach to other chromosomes. This mixing of genetic material has important results. The resultant chromosomes are lacking in ...