One of the most important bioprocessing advances in recent years has been the rise in levels of manufactured therapeutic proteins. Indeed, the overall average yield reported for commercial monoclonal ...

Mammalian cell culture is and will remain the principle vehicle for protein production in upstream manufacturing, according to Florian Wurm, Ph.D., professor of biochemistry at the University of ...

Scientist - Tumor Biology, Department for Human and Animal Cell Lines, Leibniz Institute DSMZ (German Collection of microorganisms and cell cultures) In the last decades, the upstream processing in ...

Real-time and in-line accurate measuring of protein (monoclonal antibody, or mAb) concentration has been shown across a wide dynamic range (0–135 g/L) through the ...

Modern upstream bioprocessing relies on tighter control strategies as regulators and manufacturers push toward real-time decision making. Yet the inherent variability of living cell systems makes it ...

In this interview, Kevin Broadbelt of Thermo Fisher Scientific discusses the small molecule applications of process Raman spectroscopy. How do cell therapies differ in complexity compared to ...

Continuous bioprocessing has emerged as a transformative approach in modern biomanufacturing, where integrated upstream and downstream operations enable uninterrupted production of biotherapeutics.