While the fabled fountain of youth may not actually exist, a new type of therapy now does.

Since addressing the COVID-19 pandemic, mRNA vaccines have risen as a promising tool for treating a broad range of diseases, such as cancer and genetic disorders. To be effective, foreign mRNA in ...

How do immune cells strike a balance, unleashing rapid attacks against pathogens or cancer, while avoiding damage to healthy cells? Research into an immune kill switch holds potential for controlling ...

A KAIST research team led by Professor Won Do Heo (Department of Biological Sciences) has developed an optogenetic platform, RELISR (REversible LIght-induced Store and Release), that enables precise ...

Cells in the body have to move around in order to do their jobs. During development, for instance, cells are distributed to create and grow tissue. And in the event of an immune response, different ...

Vaults are mysterious cellular structures that can be genetically engineered to store information about a cell’s history.

Genome-wide CRISPR knockout screens to identify cellular regulators of LNP-based mRNA vaccines. mRNAs encoding Green Fluorescent Protein (GFP) were in vitro transcribed (IVT) and delivered to knockout ...

Cancer cells have softer membranes than healthy cells. New nanoparticles exploit this physical difference to fuse selectively with tumors and deliver mRNA therapy with minimal off-target effects.

LNP–mRNA drug products are produced by mixing the nucleic acid drug substance with various lipid components, such as phospholipids, cholesterol, PEG–lipids and ionizable lipids, resulting in a ...

With the possibility of Robert F. Kennedy, Jr. being involved in health policy in the next administration, vaccination – especially mRNA vaccines – will become a hot topic. Is there anything to fear ...