A gene that keeps intestinal stem cells stable offers insight into how tissues repair themselves

Years before he conducted the research that would earn him a Nobel Prize in Physiology and Medicine, Shinya Yamanaka, MD, ...
STAT

Modern animal models for biomedical research remain far better than alternatives

In recent months, the Food and Drug Administration and National Institutes of Health have announced new initiatives to reduce and replace animal testing in biomedical research. Central to these ...
Nature

Beyond animal models: how organoids could transform drug development

For decades, the pharmaceutical industry has discussed moving away from in vivo models in preclinical research. Now, it’s more than a conversation. The FDA’s roadmap for reducing animal testing, ...
EurekAlert!

Natural component from licorice alleviates inflammatory bowel disease in stem cell-based model and in animals

A new study published today in Stem Cell Reports demonstrates how a human stem cell-derived model of the intestine can be ...

A black licorice compound slashes gut inflammation and cell death in IBD models and animals

A new study published in Stem Cell Reports demonstrates how a human stem cell-derived model of the intestine can be used to ...