Cell signalling pathways are central to maintaining cellular homeostasis and regulating essential functions such as proliferation, apoptosis, and repair. In both cancer and neurodegenerative diseases, ...

Researchers have identified an unexpected mechanism that links age-related stress to the decline of blood-forming stem cells.

Cancer stem cells (CSCs), a critical subpopulation within tumors, drive cancer initiation, progression, metastasis, relapse, ...

Brain cells grow faster in children with some forms of autism due to distinct changes in core cell signaling patterns, according to research from the laboratory of Anthony Wynshaw-Boris, MD, PhD, ...

A new preclinical study from Weill Cornell Medicine found that the protein caspase-5 (CASP5), long thought to be a foot ...

Throughout evolutionary history, there have been genetic elements that have duplicated - giving rise to genes with different functions. These are called 'paralogs'. They are able to form and evolve ...

Blocking the JNK pathway eased disease severity and extended survival in SMA mice, pointing to a potential new treatment ...

Supporting cell communication processes is critical for maintaining human performance and long-term health.”— Hunter ...

A study reveals how MLKL drives stem cell aging by damaging mitochondria without causing cell death, reducing regenerative ...

• BTK inhibitors work by targeting and blocking the BTK enzyme, which is crucial for the survival and growth of cancerous B-cells in mantle cell lymphoma (MCL). This cuts off the cancer cell’s support ...