The framework predicts how proteins will function with several interacting mutations and finds combinations that work well ...

The search space for protein engineering grows exponentially with complexity. A protein of just 100 amino acids has 20^100 ...

Fusion oncoproteins arise when a gene fuses with another gene and acquires new abilities. Such abilities can include the formation of biomolecular condensates, "droplets" of concentrated proteins, DNA ...

The search space for protein engineering grows exponentially with complexity. A protein of just 100 amino acids has 20100 ...

Industrial yeasts are a powerhouse of protein production, used to manufacture vaccines, biopharmaceuticals, and other useful ...

Researchers led by Xian-Yang Qin at the RIKEN Center for Integrative Medical Sciences (IMS) in Japan have developed a score that predicts the risk of liver cancer. Published in the scientific journal ...

For decades, scientists have relied on structure to understand protein function. Tools like AlphaFold have revolutionized how researchers predict and design folded proteins, allowing for new ...

Researchers in the Nanoscience Center at the University of Jyväskylä, Finland, have developed a pioneering computational model that could expedite the use of nanomaterials in biomedical applications.

CGSchNet, a fast machine-learned model, simulates proteins with high accuracy, enabling drug discovery and protein engineering for cancer treatment. Operating significantly faster than traditional all ...

Researchers found that paired pathogenic variants can restore protein function rather than make it worse. This phenomenon ...

A generalizable ML framework predicts protein interactions with ligand-stabilized gold nanoclusters, supporting faster design of bioimaging, sensing and drug delivery materials. (Nanowerk News) The ...