Medscape

Molecular Imaging and Carbonic Anhydrase IX-targeted Radioimmunotherapy in Clear Cell Renal Cell Carcinoma

Conventional imaging is suboptimal at evaluating disease status in renal cell carcinoma (RCC) because of poor sensitivity. Furthermore, there is an unmet need for the treatment of metastatic RCC, both ...
Medscape

Phase I Trial of Sunitinib Malate Plus Interferon-α for Patients With Metastatic Renal Cell Carcinoma

Background: Sunitinib malate is an oral, multitargeted tyrosine kinase inhibitor that has demonstrated superior efficacy over interferon (IFN)-α in a phase III trial in first-line, metastatic renal ...
ascopubs.org

Overall survival (OS) in renal cell carcinoma (RCC) before and after the introduction of targeted therapies (TTs): A Norwegian population-based study (2000–2011).

Specificity of radiographic lymphadenopathy for lymph node metastasis in renal cell carcnioma. This is an ASCO Meeting Abstract from the 2015 Genitourinary Cancers Symposium. This abstract does not ...
ascopubs.org

Evaluating Overall Survival and Competing Risks of Death in Patients With Localized Renal Cell Carcinoma Using a Comprehensive Nomogram

Many patients with localized node-negative renal cell carcinoma (RCC) are elderly with competing comorbidities. Their overall survival benefit after surgical treatment is unknown. We reviewed cases in ...
Nature

Differential regulation of LncRNA-SARCC suppresses VHL-mutant RCC cell proliferation yet promotes VHL-normal RCC cell proliferation via modulating androgen receptor/HIF-2α/C ...

It is well established that hypoxia contributes to tumor progression in a hypoxia inducible factor-2α (HIF-2α)-dependent manner in renal cell carcinoma (RCC), yet the role of long noncoding RNAs ...