A complement C4 (also known as a complement component 4, or simply C4) is a test to measure the level of C4 proteins you have in your blood. These proteins play a role in how your immune system ...

Among people with sickle cell disease—an inherited blood disorder—acute chest syndrome (ACS) is the leading cause of death. The condition is the result of red blood cells becoming stiff, sticky, and ...

In myasthenia gravis, complement plays a big role in what happens to the muscle end of the neuromuscular junction, explains Miriam Freimer, MD, an author on 5 abstracts presented at the recent 15th ...

While retrieval-augmented generation is effective for simpler queries, advanced reasoning questions require deeper connections between information that exist across documents. They require a knowledge ...

This year marks the hundred-and-seventy-fifth anniversary, or demisemiseptcentennial, of “Moby-Dick,” originally published in 1851. (Saving you the math.) Is it O.K. to have a “Moby-Dick” T-shirt for ...

The authors do not work for, consult, own shares in or receive funding from any company or organization that would benefit from this article, and have disclosed no relevant affiliations beyond their ...

The original version of this story appeared in Quanta Magazine. Much of mathematics is driven by intuition, by a deep-rooted sense of what should be true. But sometimes instinct can lead a ...

The alternative complement pathway plays a key role in the pathogenesis of IgA nephropathy. Iptacopan specifically binds to factor B and inhibits the alternative pathway. In this phase 3, double-blind ...