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Complement System Pathways
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5:46
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Demystifying Medicine McMaster
The Complement System
The complement system is part of the immune system. Its main function is to guide phagocytic cells and clear microbes and damaged cells from an organism. In this video, we introduce the role of C3 protein and how the protein can kill bacteria with/without the help from the other parts of the immune system. The video ends with an illustration of ...
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0:26
✨Complement Coagulation Pathway✨ 🔸Interconnection between two major plasma cascade systems in the body: the Complement system (innate immunity) and the Coagulation system (blood clotting). 💐Complement Pathway💐 3 activation routes, all converging at the formation of C3 convertase → C5 convertase → Membrane Attack Complex (MAC, C5b–9): 🔸1.Classical pathway → triggered by Ag–Ab complexes (IgG, IgM) 🔸2.Lectin pathway → triggered by Mannose-binding lectin (MBL) 🔸3.Alternative pathway → triggere
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