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northwestern.edu
Single Cell Top-Down Proteomics
Single cell top-down proteomics of 10,000 cells. Here we introduce single-cell Proteoform Imaging Mass Spectrometry (scPiMS) now published in Nat. Biotech. which measures intact proteoforms directly from 10,809 single cells from a rat hippocampus. This new platform addresses the throughput bottleneck for single cell proteomics using mass ...
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