Dr. Xanthine on Instagram: "original vid source nucleus medical media, original audio by chandler, spotlight from paternoga & wilson in molecular cell, 2023 " During translation initiation in eukaryotes, the small ribosomal 40S subunit forms a 43S pre-initiation complex (PIC) with eukaryotic initiation factors (eIFs) 1, 1A, 2, 3, 5, and the initiator methionyl-tRNA (Met-tRNAi)2,3 (Figure 1A). The 43S PIC is recruited to the 5′ end of the capped mRNA by the eIF4F complex and then scans through th