Video: Factors Influencing Bioavailability: First-Pass Elimination
jove.com
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7.4K Views. When a drug is taken orally, it undergoes a journey starting from the gastrointestinal (GI) tract, passing through the portal vein, reaching the liver, and finally entering the systemic circulation. This process involves the absorption of the drug across the GI tract. The liver is the primary site for metabolizing the drug, with ...
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