Molecular actions of the PML-RARα fusion protein in promyelocytic leukaemia
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Molecular actions of the PML-RARα fusion protein in promyelocytic leukaemia
The naturally occurring retinoic acid isomers 13-cis-retinoic acid and all-trans-retinoic acid (ATRA) influence processes of morphogenesis and differentiation. The effect of retinoic acid is mediated via the retinoic acid receptors α, β and γ (RARα, RARβ, RARγ). In the absence of ligands, retinoic acid receptors repress transcription by ...
17.1K viewsFeb 22, 2010
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