Congratulations to five amazing winners of this year’s Breakthrough Prize in Life Sciences: Jeffrey M. Friedman, F. Ulrich Hartl, Arthur L. Horwich, David Julius and Virginia Man-Yee Lee. Their discoveries range from the regulation of appetite to the sensation of pain, the mechanisms of protein folding, and the connections between protein tangles and neurodegenerative disease. Tune in to see them receive their prizes at the Breakthrough Prize ceremony on the National Geographic channel November